Consumption of nattokinase was associated with a reduction in both systolic and diastolic BP. The reduction in systolic BP was seen for both sexes but was more robust in males consuming nattokinase. The average reduction in diastolic BP in the nattokinase group from...

European Food Safety Authority (EFSA), Parma, Italy. Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the fermented soybean extract NSK-SD® as a novel food (NF)...

Our aim was to determine the quantitative effects of a single-dose of Nattokinase (NK) administration on coagulation/fibrinolysis parameters comprehensively in healthy male subjects. A double-blind, placebo-controlled cross-over NK intervention study was carried out...

The objective of this study was to examine the effects of nattokinase supplementation on blood pressure in subjects with pre-hypertension or stage 1 hypertension. In a randomized, double-blind, placebo-controlled trial, 86 participants ranging from 20 to 80 years of...

This white paper describes the biological activity and safety of the enzyme called nattokinase. The paper focuses on the proprietary product produced by Japan Bio Science Laboratory Co, Ltd of Japan (JBSL), NSK-SD® (Natural Super Kinase-Sprayed Dried). The activity...

This is a study conducted by Japan Bio Science Laboratory Co Ltd (JBSL) to examine the improvement of blood flow in human participants after consuming the fermented soybean extract NSK-SD® (Nattokinase) - a proprietary and patented product manufactured by JBSL in...